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What’s the Difference Between Type 1 and Type 2 differences between Type 1 and Type 2 diabetes. Guideline title Guidelines for Improving the Care of Older Adults With Diabetes Mellitus: 2013 Update. Diabetes mellitus (MEL-ih-tus) often referred to as diabetes is characterized by high blood glucose (sugar) levels that result from the body’s inability to produce enough insulin and/or effectively utilize the insulin. HumaPen Luxura Insulin Delivery Device.